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ScienceDaily (July 2, 2012) ? Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.
While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.
The research is published in the July edition of the peer-reviewed journal Basic Research in Cardiology.
"This very early study may help us identify and better understand the mechanisms involved in the higher risks of heart disease during pregnancy and may provide new opportunities to better treat pregnant women with cardiovascular complications and risk factors," said senior study author Dr. Mansoureh Eghbali, an assistant professor of anesthesiology at the David Geffen School of Medicine at UCLA.
For the study, researchers assessed heart differences after heart attacks among late-stage pregnant female rats and non-pregnant animals. They found that the pregnant animals' hearts demonstrated poor functional recovery, with only 10 percent restoration of heart function, compared with 80 percent restoration among the non-pregnant group. The pregnant animals also had a four-fold increase in damaged heart tissue over the non-pregnant group.
"We observed worse heart function and a greater area of damage in hearts from the late-pregnancy group, compared to the non-pregnant group," said first author Dr. Jingyuan Li, a postdoctoral fellow in the department of anesthesiology at the Geffen School of Medicine.
"These findings show that the heart in late pregnancy may be particularly vulnerable to the type of injury caused by a heart attack," Eghbali said.
Surprisingly, one day after giving birth, the formerly pregnant animals' heart function was partially restored; after seven days, their heart function was almost fully restored to the levels of the corresponding non-pregnant state.
Researchers took a closer look to see what mechanisms were behind the heart's inability to effectively recover after such a cardiac event in late pregnancy.
After a heart attack -- caused by a lack of blood flow to the heart -- the reintroduction of blood to the affected area can sometimes lead to problems, a phenomenon known as reperfusion injury, they said. When the blood hits the oxygen-starved tissue, it can result in a sudden increase in oxygen radicals that cause cell damage.
The research team found that in late pregnancy, several components of this process are especially aggravated, including the dysfunction of mitochondria, which are key cellular sub-units that are involved in cell death, and the reduction of signaling proteins that protect the heart against reperfusion injury.
Eghbali noted that the next stages of research will focus on understanding in more detail why the heart in late pregnancy is at a higher risk for coronary heart disease and will explore interventions and identify promising candidates for drug therapy.
The study was funded by the National Institutes of Health (grants HL089876, HL089876S1, HL077440 and HL088975).
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The above story is reprinted from materials provided by University of California - Los Angeles Health Sciences, via Newswise.
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Source: http://www.sciencedaily.com/releases/2012/07/120702162401.htm
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Japan whistleblower wins in Supreme Court in nation first as judge dismisses Olympus appeal
TOKYO - Japan's Supreme Court has ruled in favour of a whistleblower for the first time in a case that highlights the harsh treatment outspoken employees have endured in a nation that zealously values loyalty and conformity.
Despite being a good salesman with experience in the United States, Masaharu Hamada, 51, was demoted at Olympus Corp., forced to take rudimentary tests and ignored by colleagues, in what he alleged was reprisal for raising the issue of supplier complaints.
He received a notice Saturday from this nation's highest court, dated Thursday, dismissing the appeal by Tokyo-based camera and medical equipment maker Olympus of a 2010 lower court decision. It sealed the victory of the little "salaryman" against a giant of Japan Inc.
"We need a society where honest hard-working people don't lose out," Hamada told The Associated Press. "This is about justice and human rights."
Hamada's story highlights how workers labeled as misbehaving are punished in Japan, where major companies like Olympus offer lifetime employment, although they more freely fire contract and part-time workers.
That means employees like Hamada become targets of cruel harassment designed to silence them or make them quit. Hamada was nearly driven to breakdown during his five-year battle.
Japan is behind some Western nations in protecting whistleblowers. A law to protect them was enacted only in 2006, and critics say it is inadequate because it does not penalize companies that punish whistleblowers. To pursue legal action, whistleblowers can't quit as the law only applies to employees.
Only a handful of whistleblower has come forward in Japan in the past few decades. When they do, they are treated as outcasts, sometimes being told to sit in closet-sized offices or to mow the lawn. Sometimes even their children become victims of discrimination. So abhorred is the employee who dares to question the company.
Hamada sued Olympus in 2008, saying he was punished for relaying a supplier's complaint that its best employees were being lured away by Olympus. Olympus said he was merely transferred, not demoted.
His case is considered a whistleblowing case in Japan because he went first to his bosses and then to the company compliance unit, trying to raise questions about the professional behaviour of colleagues for the public good, and, as the Supreme Court found, was punished unfairly in retribution.
Last year, the Tokyo High Court reversed an earlier district court decision and ordered Olympus to pay Hamada 2.2 million yen ($28,000) in damages for the transfer. Olympus had appealed.
Olympus was not immediately available for comment Saturday. In the past, it has called the court rulings favouring Hamada "regrettable."
Olympus has been targeted recently by another high-profile whistleblower, Briton Michael Woodford, the former chief executive.
Woodford was fired in October after he blew the whistle on dubious accounting at Olympus. The company later acknowledged it hid 117.7 billion yen ($1.5 billion) in investment losses dating back to the 1990s. Three former Olympus executives, including the ex-chairman, were arrested earlier this year on suspicion of orchestrating the accounting coverup.
Woodford has become a hero in Japan. Three weeks ago, Woodford won a 10 million pound (1.2 billion yen, $15.4 million) settlement from Olympus in a British court. He had sued alleging unlawful dismissal and discrimination as he was not given the same treatment as a Japanese employee.
How Hamada will be treated at Olympus on Monday remains unclear.
He plans to show up at work at 8:45 a.m. as usual, wearing his company colour, blue, as he is confident he is an upstanding "Olympus-man."
Hamada said he would like to be transferred to the corporate compliance division, given the serious problems that have surfaced with Woodford's case and the knowledge he has gained about proper management through his court battle.
"I would like to work for the true revival of Olympus, where dedicated employees can work and feel joy, in a nurturing environment, and be proud," said Hamada.
___
Follow Yuri Kageyama on Twitter at http://twitter.com/yurikageyama
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LOS ANGELES, CA - JULY 01: Singer Beyonce attends the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Christopher Polk/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Meagan Good arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
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LOS ANGELES, CA - JULY 01: Rapper Big Sean arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Actor Hosea Chanchez arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Michelle Williams arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
Tamar Braxton arrives at the BET Awards on Sunday, July 1, 2012, in Los Angeles. (Photo by Jordan Strauss/Invision/AP)
LOS ANGELES, CA - JULY 01: TV Personality Lala Anthony arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: TV Personality Lala Anthony (shoe detail) arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Rapper MC Lyte arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actor Boris Kodjoe arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Host Samuel L. Jackson and Latanya Richardson arrive at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Rapper LoLa Monroe arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Rapper LoLa Monroe arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Jessica Reedy arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Maury Phillips/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Regina King arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Rapper Machine Gun Kelly arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
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LOS ANGELES, CA - JULY 01: Singer Amber Bullock arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Amber Bullock arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Rapper 2 Chainz arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Yolanda Adams arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Rapper Tyga arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Willow Smith (L) and actor Jaden Smith arrive at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Monica (R) and husband Shannon Brown arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Jaden Smith arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Taraji P. Henson arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Taraji P. Henson arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Kenya Moore arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Maury Phillips/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Musician Jennah Bell arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Trey Songz arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Radio DJ Donnie Simpson arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Angela Bassett arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Angela Bassett arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Maury Phillips/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Chairman and Chief Executive Officer of BET Networks Debra Lee arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Model Toccara Jones arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Tamia attends the 2012 BET Awards Ford Hot Spot at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Maury Phillips/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Tamia attends the 2012 BET Awards Ford Hot Spot at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Maury Phillips/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actor Barry Floyd arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Model Melyssa Ford and recording artist Flo Rida arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Reverend Al Sharpton arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer/song-writer Lira arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actor RonReaco Lee arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Ray J arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actress Eva Marcille arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Usher attends the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Alberto E. Rodriguez/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Actor Laz Alonso arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Frankie Beverly arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Comedian Mike Epps (R) arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Jason Merritt/Getty Images For BET)
LOS ANGELES, CA - JULY 01: Singer Chaka Khan arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Singer Luke James (R) and guest arrive at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Model Selita Ebanks arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: Actor Jamie Foxx arrives at the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Mark Davis/Getty Images for BET)
LOS ANGELES, CA - JULY 01: (L-R) Singer Beyonce, rappers Jay-Z and Kanye West and television personality Kim Kardashian attend the 2012 BET Awards at The Shrine Auditorium on July 1, 2012 in Los Angeles, California. (Photo by Christopher Polk/Getty Images For BET)
Source: http://www.huffingtonpost.com/2012/07/01/bet-awards-red-carpet-2012_n_1641842.html
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?After 29 years of marriage, raising four children to adulthood and planting a thriving church during those years, my wife and I know that marriage requires intentional commitment. A marriage will not do well without focus on building a strong relationship.
The pastor who married us gave me one line of advice: ???
Check out the rest of my column in Lehigh Valley?s Newspaper:?The Morning Call of Allentown, Pennsylvania:
Faith and Values: Marriage 101: How to maintain a strong relationship
Excerpts from the column:
?There are no perfect marriages. All married people struggle to some extent to keep their marriages healthy and strong. I say this because I find that many people want too much from marriage. They have unrealistic ideas about marriage. They?re in love with the idea of being in love.?
?It?s one thing to be in love; it?s another to love a person in the proximity of marriage! Unrealistic and idealized versions of the relationship of marriage or of the person you plan to marry will quickly shatter in married life.?
?When sinners say, ?I do? we cannot expect perfection! There are risks involved because there are sinners involved. You will probably get hurt but what you do with the hurt is the important part. The key to marital harmony is not the removal of all conflict but a shared commitment to a reconciling spirit between two people who have been reconciled to God.?
?Marriage is not primarily about personal happiness and satisfaction. Yes, in good marriages, this will be experienced. But personal happiness and satisfaction must not be viewed as the goal of marriage if you hope to experience them in it. God designed us so that our deepest joys are experienced in giving love.?
?Marriage clearly offers the closest possible relationship of intimacy and companionship we can enjoy. It should be a relationship of mutual encouragement, acceptance and partnership. It should be characterized by truth, love, good will and grace toward each other.?
Steve Cornell
Be the first to like this.
Steve Cornell is founding and senior pastor of Millersville Bible Church, Millersville Pennsylvania (USA) (a position he has held for more than 27 years). His ministry also includes daily and weekend radio. Steve is a correspondent for Lancaster Newspapers Inc. and writes for the Morning Call of Allentown, Pennsylvania. He is a recipient of six writing awards from the Amy Foundation. Steve especially enjoys ministry among the students at the State University in Millersville. Steve and his wife Becky have four adult children, a wonderful daughter-n-law, a great son-n-law and a precious granddaughter! ????? ?? ???? ??? ?? ?????????? This entry was posted in Marriage, Broken Relationships, Relationships, Wives, Divorce and Remarriage, Life of a pastor, Family life, Steve Cornell, Counseling, Divorce, Wedding. Bookmark the permalink.Source: http://thinkpoint.wordpress.com/2012/06/30/marriage-101-how-to-maintain-a-strong-relationship/
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Home ? DataSAC Inc. Hiring Business Change Management Specialist In Toronto ON Job Title : Business Change Management Specialist
Company : DataSAC Inc.
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Location : Toronto, ON
Date : 2012-06-28 06:53:50
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El Paso businessman Paul Foster, foreground, joined businessman Woody Hunt, to his left, outside city council chambers Tuesday after council voted to build a baseball stadium to host a Triple A baseball team that they plan to purchase and bring to El Paso. At left is Hunt's son, Joshua Hunt.
El Paso must now wait on Pacific Coast League officials and team owners to determine whether the Sun City will again be home to affiliated professional baseball.
MountainStar Sports Group -- the local ownership group pursuing a team -- on Friday made a presentation to the Pacific Coast League Executive Committee in Dallas trying to sell El Paso as a home for Triple-A baseball.
No decision was made, and no timetable has been set for an answer, the local investors said.
If the league does not approve El Paso and the ownership group, the city will not obtain a baseball team.
"We spent a very productive three hours with the Pacific Coast League today," Josh Hunt, a member of MountainStar Sports, said in a prepared statement. "We believe we made a positive, compelling case for El Paso as a viable Triple-A baseball market, and we hope for a favorable response."
The Pacific Coast League, one of two Triple-A leagues, said it had no comment. Generally, the league takes a few weeks to review and research sales and relocations.
The league's public relations and operations assistant, Dylan Higgins, described the process of sale and relocation as complex. There must be a team for sale, because new ones cannot be created; a viable ownership group; and an arrangement with the new city, which requires the proper facilities, he said, and the league must sign off on the deal.
El Paso appears to have three of the four crossed off the checklist.
Prominent businesspeople
Woody Hunt, Paul Foster, Joshua Hunt and Alejandra De La Vega Foster make up the MountainStar Sports Group. The City Council on Tuesday committed to build a $50 million Downtown baseball stadium if a team is secured. The Tucson Padres, a Triple-A affiliate of Major League Baseball's San Diego Padres, is for sale. Triple-A is the closest level to Major League Baseball."In some ways, those first few pieces of the puzzle were the most difficult," said city Rep. Cortney Niland, who added that the stadium, though the term sheet has been approved, would not be built unless a team is secured. "Now, this is the last hurdle. Unfortunately, it's out of our hands, and we're all very anxious."
El Paso also took steps to make sure its pitch conformed to the Pacific Coast League's preferences. They included a Downtown stadium -- and the need to raze City Hall -- and a non-compete clause, despite already having the Diablos, whose ownership just put $750,000 in renovations into city-owned Cohen Stadium.
"We feel the city did everything we could to make a strong pitch," Niland said.
The key concerns could be security, given El Paso's proximity to Mexico, and marketability, Niland said.
Besides the local ownership group, consultants Alan Ledford, founder of Perfect Game Ventures LLC, and Dan Barrett, principal of Barrett Sports Group LLC, spoke in support of Triple-A baseball in El Paso.
"We believe we thoroughly addressed all of the league's questions, and presented the many good attributes of our city," Hunt said.
If the Pacific Coast League approves a team for El Paso, officials hope to begin play in 2014, depending on the construction of the ballpark.
MountainStar Sports Group, despite the waiting time, continues to prepare for a baseball team in El Paso. The group has secured several websites, including ElPasopadres.com. The name, which is registered to Franklin Mountain Management, owned by Foster and Scott Weaver, provides another clue that the team that could come to El Paso is the Tucson Padres.
ElPasopadres.com showed a silhouette of a baseball player with a yellow sun and the iconic Star on the Mountain at the top right. Later in the evening Friday, the website was a blank orange. Other websites owned by the group include elpasobaseball.com and elpasotripleA.com.
Evan Mohl may be reached at emohl@elpasotimes.com; 546-6381. Follow him on Twitter @EvanMohl.
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